With the recent developments in big data and deep learning, a variety of traffic information is collected widely and used for traffic operations. In particular, long short-term memory (LSTM) is used in the field of traffic information prediction with time series characteristics. Since trends, seasons, and cycles differ due to the nature of time series data input for an LSTM, a trial-and-error method based on characteristics of the data is essential for prediction models based on time series data in order to find hyperparameters. If a methodology is established to find suitable hyperparameters, it is possible to reduce the time spent in constructing high-accuracy models. Therefore, in this study, a traffic information prediction model is developed based on highway vehicle detection system (VDS) data and LSTM, and an impact assessment is conducted through changes in the LSTM evaluation indicators for each hyperparameter. In addition, a methodology for finding hyperparameters suitable for predicting highway traffic information in the transportation field is presented.